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This is especially important for patients with absorption issues such as those with digestive conditions, low stomach acid (common with aging), or MTHFR gene variants who cannot adequately absorb B12 from food or oral supplements

Thyroid Function and Hair Health Thyroid hormones directly regulate hair follicle cycling, making thyroid function tests essential in hair loss evaluation

Meanwhile, low-density lipoprotein receptor-related protein 1 (LRP1) is particularly relevant to AD pathophysiology because of its involvement in lipid trafficking and amyloid- clearance, offering the dual advantage of facilitating drug transport while potentially influencing disease mechanisms (Petralla et al., 2024a)

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Its important to note that these symptoms can vary in severity and may not always be directly attributed to Vitamin B12 deficiency