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Bengio, H

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A widely cited 2003 paper by Anisimov and Khavinson reported a ~12% increase in mean lifespan in female CBA mice receiving Epitalon over multiple courses

DHA and EPA down-regulate COX-2 expression through suppression of NF-kappaB activity in LPS-treated human umbilical vein endothelial cells

For example, the integration of metabolomics and transcriptomics has revealed a strong correlation between specific metabolic pathways and changes in gene expression, providing valuable insights into the biological mechanisms of depression [402]