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In this randomized, comparative trial, 90 patients with ME/CFS were given either 2 grams per day of Acetyl-L-Carnitine (ALCAR), 2 grams per day of Propionyl-L-Carnitine (PLCAR), or a combination of both over a 24-week period

The cohort included 82% males and 18% females, and children with genetic syndromes, prematurity, major medical disease or severe irritability were excluded, although common comorbidities such as gastrointestinal, allergic, neurological, and sleep disorders were present

10.1186/1477-7525-8-22 102 MoeinzadehA

The basal ganglia (especially the pallidum) were the most frequently affected areas in MMA patients

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