hypothesis glutathione persister cells

hypothesis glutathione persister cells Drug-tolerant in cancer: the cutting edges and future directions Glutathione peroxidase 4‐dependent glutathione high‐consumption

Name: hypothesis glutathione persister cells Drug-tolerant in cancer: the cutting edges and future directions Glutathione peroxidase 4‐dependent glutathione high‐consumption
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Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library hypothesis glutathione persister cells Identification and genetic dissection of convergent cell states Role of Glutathione in Cancer: Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death JCI CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione GPX4 Frontiers Exogenous cystine increases susceptibility of drug resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels

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& Cambron, S

H.PostS.CreightonC

have revealed that ferroptosis regulates PD-L1 expression in HNSCC through a dual mechanism: on the one hand, PD-L1 is upregulated via the ROS-driven NF-B signaling pathway (a membrane damage-independent pathway), and on the other hand, immune checkpoint molecule expression is promoted through ferroptosis stress-induced calcium influx (a membrane damage-dependent pathway)