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The above procedure was repeated with inhibitor concentrations spanning 0.3-60 M to determine the effective concentration (EC50) required to inhibit 50% NNMT activity in cultured adipocytes

References 1 Bioorganic & Medicinal Chemistry Letters (PubMed)Raun et al

Li H, Horke S, Forstermann U (2014) Vascular oxidative stress, nitric oxide and atherosclerosis

"FDA: Acetaminophen doses over 325 mg may lead to liver damage"