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Therefore, using Riluzole to target and block glutamate transport, in combination with chemotherapy and immunotherapy, has become a promising clinical research direction for overcoming resistance [227]

doi: 10.3389/fmicb.2022.798853 122 ThanabalasuriarAScottBNVPeiselerMWillsonMEZengZWarrenerPet al

Furthermore, oncogenes are originally believed to elevate the ROS levels in cells, supported by the facts that ectopic expression of different oncogenes (e.g., Myc and KRAS) increase ROS levels in cells [6, 7]

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