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10.3390/biom11081144 5 Aranda-RiveraA

doi: 10.1016/j.freeradbiomed.2005.02.026 5 LeeSKimSMLeeRT

It serves as an excellent substrate for testing extracellular matrix (ECM) remodelling, angiogenic upregulation, and the modulation of cellular inflammatory pathways under induced stress

Increased numbers of GM-CSF-producing CD4 and CD8 lymphocytes, as well as increased numbers of IL-17A+GM-CSF+ double-producing CD4, CD8, and NK cells have been found in the blood and joints of patients with SpA, suggesting a possible role also for GM-CSF in AS pathogenesis