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It facilitates the production of lymphocytes, a type of white blood cell involved in immune responses

The compound then received GRAS (Generally Recognized as Safe) designation from the FDA for use as a food ingredient, which is a separate regulatory category from drug approval

J Diet Suppl 21:112 Chappell AJ, Allwood DM, Johns R, Brown S, Sultana K, Anand A et al (2018b) Citrulline malate supplementation does not improve german volume training performance or reduce muscle soreness in moderately trained males and females

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Histochem Cytochem 63 , 575591 (2015)