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Polynucleotide and Polypeptide Variants The present invention also encompasses variants (e.g., allelic variants, orthologs, etc.) of the polynucleotide sequence disclosed herein in SEQ ID NO:1, the complementary strand thereto, and/or the cDNA sequence contained in the deposited clone

[DOI] [PubMed] [Google Scholar] 224.Hua D, Cai D, Ning M, Yu L, Zhang Z, Han P, et al

Ethics statement All aspects of the animal studies and all protocols met the accepted criteria for the care and experimental use of laboratory animals, and were approved by the Animal Research Committee of the 1st Faculty of Medicine, Charles University in Prague (under registration No

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These shifts can disrupt nutrient absorption and metabolism, interfere with insulin signaling, and enhance inflammatory responses, thus heightening T2DM risk ( Overview of AMPK signaling pathways Adenylate-activated protein kinase (AMPK), also known as AMP-dependent protein kinase, is a pivotal element in diabetes research and other metabolism-related disorders