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Enhanced tumor targeting and penetration of proteolysis-targeting chimeras through iRGD peptide conjugation: a strategy for precise protein degradation in breast cancer

An equal number of male and female mice 812 weeks old were used for each experiment

ERK1 (p44 MAPK) and ERK2 (p42 MAPK) are activated due to the increased presence of ROS (140)

MA, CO'D and PT checked the references, PM and CO'D assessed the quality of included studies and the draft was reviewed by MA, CO'D, PT and MF

However, current COVID-19 therapies are limited, as they often target either free radicals or inflammatory responses in isolation rather than addressing both simultaneously (120)