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Moreover, beyond the pharmacological exigencies, there are other challenges concerning its parasitic nature, such as its great genetic plasticity and adaptability, enabling it to activate a battery of genes to develop resistance quickly

For example, many studies observed mitochondrial damage in postmortem brain samples and mouse models of AD, PD and ALS 2,3

Functional genomics identify distinct and overlapping genes mediating resistance to different classes of heterobifunctional degraders of oncoproteins

doi: 10.1038/s41589-020-0472-6 32 YanBAiYSunQMaYCaoYWangJet al

Despite these microorganisms being dominant in the content of kefir grains, the microorganism content of the final product may not be the same as the grains