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Antispasmodics (e.g., hyoscyamine) and peppermint oil alleviate abnormal contractions but lack robust evidence in constipation-related pain, while laxatives improve stool passage but show limited direct analgesic efficacy

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By providing direct access to essential nutrients and hydration, it supports our patients in managing their conditions more effectively

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Neurosci Lett 424:106110 Pankratz N, Foroud T (2007) Genetics of Parkinson disease

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doi:10.1053/j.tcam.2017.10.003

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After 5 min of incubation at room temperature in plain RPMI-1640 medium, 100 nM Calcein-AM (Sigma-Aldrich, Germany) was added, and cells were incubated for 10 min at 37 C

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