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Eur J Clin Invest 48:e12997

Therefore, DNA methylation-mediated dysregulation of oxidative stress-related genes and DNA damage repair genes has emerged as a primary research focus, given its pivotal role in ARC development

Ethics declarations Conflict of Interest The authors declare no competing interests

Real world data on the risk of hepatocellular carcinoma (HCC) in CHC patients with or without cirrhosis, and benefit of surveillance in a population-based cohort is needed to guide health policy