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(From Chin WW: Current concepts of thyroid hormone action: progress notes for the clinician

The ANT is useful for the assessment of CHE/MHE, with reported areas under the curve ranging from 0.68 to 0.98, and for predicting OHE [104,105,106,107,108,109,110]

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Following discovery of a sparse number of occurrences of progressive multifocal leukoencephalopathy (PML) in those taking a FAE, median duration of FAE therapy to PML symptom onset or appearance of first PML brain lesion was 31 months (range 6110), with median duration of lymphocytopenia to PML symptoms being 23 months (range 672)