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The most advanced methods currently in clinical trials or commercially approved employ indirect targeting by immunotherapies, which focus on immune components required for MYC -driven tumors or checkpoints that are altered in MYC -driven tumors [83, 84]

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Oral intake of collagen is digested by gastric enzymes, and the resulting collagen-derived di- and tripeptides are transported through the transmembrane peptide transporter (PEPT-1) into enterocytes, where these peptides are further broken down to amino acids and then released into the bloodstream, yielding about 3960% absorption of the collagen amnio acids depending on how much the collagen was crosslinked 3,4