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Interestingly, the observed divergences in MCI1 and MCI2 glycosylation profiles reflected the different clinical follow-up of the respective class of patients: 5 MCI1 patients out 5 converted to AD within 36 months from diagnosis, while all the MCI2 subjects (6 out 6) remained stable over the time, suggesting that increasing amount of N-glycans with bisected GlcNAc is a biochemical hallmark of AD in the pre-dementia phase [2]

Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy

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It has tremendous capabilities to adapt, but these capabilities are not infinite

Cell Commun Signal 21(1):72 Guo C, Sun L, Chen X, Zhang D (2013) Oxidative stress, mitochondrial damage and neurodegenerative diseases