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Although glucagon-like peptide-1 (GLP-1) activation is reported to ameliorate oxidative stress by increasing antioxidant levels, the administration of TIR with DXN did not significantly mitigate the effects of DXN on induced cognitive impairment and oxidative stress

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Nature 435: 828833 Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT et al (2006) Augmentation of tumor angiogenesis by a Mycactivated microRNA cluster