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Trends Food Sci Technol (2017) 62:15469

doi:10.1007/s10067-007-0746-3

Activation of primary human monocytes by the oxidized form of alpha-1 antitrypsin

Conclusion: CTSD may be a possible biomarker of severe NAFLD since its hepatic/adipose tissue expression as well as circulating levels correlated with liver damage thus allowing to discriminate advanced disease