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Sudden cessation or dosage reduction can trigger withdrawal symptoms as the body adjusts

In addition, oxidized phosphatidyl cholinesmarkers of oxidative stressare detected in MS lesions, mediate OL death in culture, and induce demyelination when injected in vivo 118

"Patients will suffer from the usual side-effects of extreme tiredness, irrational behaviour, mood swings, memory problems." The British National Formulary, which sets guidelines for the use of vitamin B12 in pernicious anaemia, said the practice was based on the best available evidence base

Dangin M, Boirie Y, Guillet C, Beaufrere B

Huntington Study Group TREND-HD Investigators