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The choice of Lipoid S100 and CS concentrations was based on the results of a previous study of the authors Haidy Abbas and Manal El Sheikh that reported the preparation of luteolin loaded chitosomes and investigating their potential in Alzheimers disease management through the intranasal route [66]

[15] Glutathione: Antioxidant and Antiviral Glutathione, the most abundant cellular thiol, provides the major antioxidant defense mechanism in all mammalian cells by neutralizing toxic peroxides

Crucially, this study identified profound sex-specific differences in how this oxidative stress manifests