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This lipid peroxidation product can also alter intracellular calcium levels and mitochondrial membrane potential, further promoting the intrinsic pathway of apoptosis [42]

On the day of the assay, doxorubicin working solutions were added to injection port A of each well of the sensor cartridge (25 L)

JNJ-56136379, an HBV capsid assembly modulator, is well-tolerated and has antiviral activity in a phase 1 study of patients with chronic infection

Subsequently, 160 L of DMSO (Merck) was applied to each well, and the cells were incubated overnight