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Screening and data extraction Two reviewers (RN and AMR) independently extracted the authors name, study design (parallel or cross-over), year of publication, number of participants, baseline BMI, % female, mean age, intervention and comparator characteristics, duration and the dosage of intervention, dropouts, degree of adherence to the intervention and mean and corresponding sd of change from baseline weight in each study arm

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doi:10.1006/abio.2000.4894 Sulkowski E (1988) Macromol Symp 17:335348 Mantovaara T, Pertoft H, Porath J (1991) Biotechnol Appl Biochem 13:120126 Cai J (2000) Cereal Feed Ind 10:4142 Sulkowski E (1987) In: Liss AR (ed) Protein purification: micro to macro

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