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(Campone 2013) A large double-blind RCT (n=409) found no benefit of LC for CIPN prevention in breast cancer patients receiving taxanes

mTORC1 can regulate life span by modulating telomerase function

In vivo , intraperitoneal administration of the NRF2 activator RTA-408 significantly upregulated NRF2 expression in neurons of SOD1 G93A transgenic mice, which consequently elevated the expression of GSH, SLC7A11, and GPX4, reduced MDA and ROS levels, suppressed neuronal ferroptosis, lipid peroxidation, and mitochondrial injury, and ameliorated weight loss and motor dysfunction in mice (Yang et al., 2023)

Studies on stenohaline species gut microbiota, such as silver carp ( Hypophthalmichthys molitrix ), grass carp ( Ctenopharyngodon idella ), bighead carp ( Hypophthalmichthys nobilis ), and goldfish ( Carassius auratus ), which thrive in narrow salinity ranges, show restricted microbial changes under salinity stress

Chen D, Zhang G, Li R, Guan M, Wang X, Zou T, et al