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This interaction is essential for the reaction to occur, as it provides a pathway for the electrons to move from the nucleophile to the electrophile

doi: 10.1677/joe.0.1670505 37 ZhouLZhangMWangYDorfmanRGLiuHYuTet al

Therefore, statin therapy is not recommended for primary preventative therapy, although it can be used in possibly reducing atherosclerotic cardiovascular risks

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