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In metazoan cells, iron homeostatic mechanisms include post-transcriptional response pathways and targeted release of intracellular iron stores

Through this mechanism, they can alter chromatin accessibility and gene expression [76]

doi: 10.3390/ijms23020585 [DOI] [PMC free article] [PubMed] [Google Scholar] 160

[DOI] [PMC free article] [PubMed] [Google Scholar] Mamashli, F

Each faces a different core problem, and none of the three has generated the kind of large, long, independent evidence base that would move it out of the mixed tier