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Many common medications also deplete magnesium levels

Mitochondrial-derived reactive oxygen species and oxidized mtDNA are potent activators of the NLRP3 inflammasome, driving maturation of IL-1 and IL-18, which in turn enhance Th1 and Th17 responses essential for protection against Candida albicans and Aspergillus fumigatus (Qin et al., 2023)