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Doxorubicin and Cyclophosphamide treated rats revealed disorganization of hepatic cords and necrobiotic changes of hepatocytes

Though this cream isnt particularly lightweight, it absorbs quickly into the skin and doesnt leave a greasy residue

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Follow-up may be necessary to repeat cryotherapy or biopsy lesions that do not respond to treatment or continue to enlarge

Clinically, the lesion is a flat or slightly raised black or brown macule and may rapidly increase in size, ranging from a few millimeters to several centimeters [1, 12, 13]