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iScience 20, 489496

A significant focus was on developing inhibitors of insulin-regulated aminopeptidase (IRAP), a protein identified as the AT4 receptor, with the goal of enhancing metabolic stability and BBB permeability

Store the vial at 36-46 degrees Fahrenheit (2-8 degrees Celsius) at all times when not in use

Nat Immunol 25(4):607621 Zhang C, Qi H, Jia D, Zhao J, Xu C, Liu J, Cui Y, Zhang J et al (2024) Cognitive impairment in Alzheimers disease FAD(4T) mouse model: synaptic loss facilitated by activated microglia via C1qA

Despite promising preclinical results and its favorable safety profile, BPC 157 lacks FDA approval, necessitating further clinical trials to validate its therapeutic potential and establish comprehensive safety data