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Among peripheral organs, GABA is abundant in the pancreas, and recent research suggests that the pancreatic GABA system plays an important role in protecting the pancreas and regulating insulin metabolism 22

Extracellular ATP, often released from damaged cells, binds to the P2X7 receptor, inducing potassium efflux and leading to NLRP3 activation [35]

2 Materials and methods 2.1 Experimental mouse models In the acute SCI model, adult male C57BL/6N mice (1012 weeks, male, Nihon SLC, Shizuoka, Japan) were subjected to contusion injury at T9T10 using an Infinite Horizon Impactor (60 kdyn) or sham-operated by laminectomy only, as described previously (Figure 1A) (Scheff et al., 2003)

consists two distinct genes coding for different SOD such as FeSOD-1 and FeSOD-2 [40]

Perez-Jimenez F, et al