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doi: 10.3389/fnut.2025.1677749 Received 01 August 2025 Accepted 31 October 2025 Published 21 November 2025 Volume 12 - 2025 Edited by Jianmei Li, Nanjing Normal University, China Reviewed by Xin Geng, First Affiliated Hospital of Kunming Medical University, China Abraham Al Jody, University of Indonesia, Indonesia Ayush Kumar Srivastava, SUNY Potsdam Department of Chemistry, United States Updates Copyright 2025 Wang, Zhang, Wu, Ma, Wang and Sang

Heart failure or significant cardiac conditions: IV fluid volume can increase cardiac workload

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doi: 10.1074/jbc.M300777200 90 YangYYDengRRChenZYaoLYYangXDXiangDX

2d) revealed constitutive induction of CYP2E1 (1.8-fold) and ALDH1A1 (1.4-fold) at both protein and enzymatic activity levels in KO livers relative to WT livers (Fig