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First discovered in rat liver over 60 years ago, the cytosolic glutathione S-transferases (GSTs) are a family of dimeric enzymes that have evolved to conjugate hydrophobic and electrophilic substrates to glutathione, resulting in their inactivation and significantly increased water solubility - thus facilitating their elimination from the body

BPC stands for Body Protection Compound, and 157 refers to the particular chain of 15 amino acids that make up this peptide

Zhao et al (184) found that AF can markedly inhibit -SMA overexpression and FN deposition in the livers of rats treated with BDL and HSC activation and collagen I and III synthesis are also markedly inhibited by coadministration

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1980 Jan;110(1):130-8