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The lower section contrasts therapeutic endpointsclearance of airway secretions, resolution of bronchospasm, and adequate cardiovascular parameterswith unreliable indicators such as pupillary dilation or isolated tachycardia

Upon decreasing glutathione levels, the mice developed overt motor symptoms, and their lifespan was decreased [41]

In contrast, folate deficiency in Apolipoprotein E (ApoE)-deficient mice is reported to increase glutathione levels, possibly as a compensatory response to oxidative stress in the brain [76]

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