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Description

l-carnitine protects against arterial hypertension-related cardiac fibrosis through modulation of PPAR- expression

Individual pools and combinations were evaluated for l-carnitineTMA activity using a fractional factorial design (Figure 6B)

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A vicious cycle is created by the ensuing hyperglycemia because long-term exposure to elevated glucose levels causes glucotoxicity, which further damages -cell function and exacerbates insulin resistance (22)