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Interleukin-1 (IL-1) inhibits presynaptic 5-HT release and reduces dopaminergic neuronal activity

Li YC, Wang FM, Pan Y, Qiang LQ, Cheng G, Zhang WY, et al

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Since specific mediators driving changes in dysfunctional CD8 + T cell subsets in cirrhosis need further investigation, and their clinical relevance is yet to be fully understood, current immunotherapy strategies for cirrhosis predominantly target cells other than CD8 + T cells, such as macrophages

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