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Human exposure to NPs is still considered a scientific challenge, due to the lack of adequate methods and materials available, as well as a standardization across the analytical procedures utilized [107]

The TCM herbal monomer Danshinone IIA (Tan IIA) can alleviate kidney damage in db/db mice, possibly by inhibiting cell pyroptosis through the regulation of NLRP3 and thioredoxin-interacting protein (Txnip) expression, thus delaying the progression of diabetic kidney disease (DKD) (Wu et al., 2023a)