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Wnts, as significant messengers in the RC microenvironment, primarily contribute to cancer development through canonical Wnt signaling

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The pre-bed injection is widely considered the most important administration window, as it amplifies the body's largest natural GH pulse during deep sleep

The experimental setup and the therapeutic regimen closely mirror those used in most previously published SCLC xenograft studies, with the key difference that we extended monitoring of tumor-free survival (time to recurrence) for an additional 4 months beyond the end of treatment to detect delayed recurrence (Fig

Moderation and assessing individual risk are key