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Consequently, its activity reflects the cells energy state and redox balance and can modulate mitochondrial ROS production under conditions of high NADH/NAD + ratios or impaired electron flow

Microglia with depleted GSH have an exacerbated ROS/RNS production, elevated pro-inflammatory cytokine release, impaired phagocytic clearance, and increased neurotoxic output (Lee et al., 2010)

Indeed, sialic acid production, used for capsule biosynthesis and LOS modification, is fueled by lactate

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Timeline by Use Type Here is how the ranges break down by what is being treated