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FIGURE 1 We next verified whether [GSH] i modulation effectively altered cell sensitivity toward oxidative stress

O 2 is the main initial product of ROS, typically produced from electron leakage in the mitochondrial respiratory chain and stored in the mitochondria during cellular diffusion [42,43,44]

However, there were no statistically significant distinctions in the reduction of IL8 between the groups

However, its relative impact on overall intraepithelial cell levels of GSH, or activation of other proinflammatory mediators, is unclear and requires further study