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In acute hyperammonemia, the activation of NMDA receptors increases the ingress of sodium and Ca 2+ , with the latter activating calcineurin, which dephosphorylates and activates Na + /K + ATPase, which, in turn, extracts sodium and increases the ingestion of ATP, while the mitochondria absorb the excess calcium (Natesan et al., 2016), reducing ATP synthesis in mitochondria by altering the homeostasis of Ca 2+

Somatic Mutations in TP53 Identified in T-Cells of Patients with TP53-mutated AML, 2022

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Tan (Singapore, Singapore) Objective: To determine if the 12item Brief Smell Identification Test (BSIT) is a suitable screening tool when compared with the 40item University of Pennsylvania Smell Identification Test (UPSIT) to ascertain olfactory dysfunction (OD) in a Singapore cohort

Expert Opin Drug Deliv 20(11):15951607