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Disclosures: Chandana Thimme Gowda: Nothing to Disclose, MALLIKARJUNA SIRAGANAHALLI ESHWARAIAH: Nothing to Disclose, Nirmala Mavila: Nothing to Disclose, Jiaohong Wang: Nothing to Disclose, Maria Lauda Tomasi: Nothing to Disclose, Komal Ramani: Nothing to Disclose 1574 INTEGRATED HEPATOLOGY AND ADDICTION MEDICINE CONSULTATION FOR HOSPITALIZED PATIENTS WITH ALCOHOL USE DISORDER REDUCES FUTURE LIVER-RELATED DECOMPENSATING EVENTS Jay Luther 1 Paul George 2 Michael Butler 2 Prasanna Challa 2 Esperance Schaefer 3 Russell Goodman 1 Wei Zhang 2 , 1 Massachusetts General Hospital, 2 MGH, 3 BWH Background: While multiple factors contribute to rising mortality seen with alcohol-associated liver disease (ALD), one deficiency is clear: most patients with ALD are diagnosed at an advanced stage

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244 Targeted conditional knockout of GPx4 in forebrain neurons of adult mice causes AD-like cognitive impairments and neurodegeneration that can be attenuated by ferroptosis inhibitors

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