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551 The NR repletion increases the levels of UPRmt-related proteins and promotes the clearance of mutant hSOD1 neurotoxic protein

For example, excessive doses of the copper ionophore elesclomol can flood cells with copper, overwhelming antioxidant defenses and triggering lethal oxidative stress [247] whereas excessive copper supplementation can cause overload and ROS-mediated damage [248]

The thiol is weakly acidic (intrinsic p K a 9.0-9.5), its the dissociation leaves the thiolate anion

It is not intended to diagnose, treat, cure, or prevent any disease