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In the BRAF mutant cell lines M229P and M238P, we observed that cell lines begin with different initial differentiation stages as defined by their subtype signatures, but shift notably towards the undifferentiated signature upon acquired resistance to vemurafenib (M229R, M238R) (Figure 2A)

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9 1067-1082 1996 Rattus norvegicus, Mus musculus, Felis catus, Homo sapiens, Ursus sp., Xenopus sp

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