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A diagnosis of PA first requires demonstration of megaloblastic anemia by conducting a full blood count and blood smear, which evaluates the mean corpuscular volume (MCV), as well the mean corpuscular hemoglobin concentration (MCHC)

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Dosage levels: High doses can lead to headaches or nausea

Direct confrontational testing was limited because of limited cooperation, but JC was able to give symmetric resistance with bilateral hip flexion

Trial data at the 2 mg/week dose (lower end of Phase 2) ran somewhat below the 4 mg+ doses