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Furthermore, they validated that this analgesic effect was linked to a reduction in inflammation, a mechanism corroborated by multiple studies demonstrating UAs anti-inflammatory properties in chondrocytes (56, 57)

Instead of only allowing fully digested nutrients to pass through, the compromised barrier allows endotoxins (such as lipopolysaccharides, or LPS, from the cell walls of gram-negative bacteria), undigested food proteins, and microbial fragments to "leak" directly into the bloodstream