glutathione zinc deficiency causes acute impairment of metabolism followed by coordinated antioxidant defenses amplification in gills of brown mussels Perna perna Frontiers | Functions and strategies

In addition, there were nine genes encoding unknown functional proteins significantly upregulated in the recombinant strain, which may play an important role in the resistance of the recombinant strain to an acid stress environment

Weissbach H, Etienne F, Hoshi T, Heinemann SH, Lowther WT, Matthews B, St John G, Nathan C, Brot N (2002) Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function

Alcohol is one of the main factors that alters the proper functioning of the gut, leading to a disruption of the intestinal barrier integrity that increases the permeability of the mucosa with a trend for a depletion of bacteria with anti-inflammatory activity, such as Bacteroidetes and Firmicutes phyla, and an increase in bacteria with pro-inflammation activity, such as Proteobacteria (Mutlu et al., 2012)

doi: 10.3389/fimmu.2015.00111

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