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Cancer cells adapt to the harsh conditions within the TME by modifying their metabolic pathways to support rapid proliferation, evade immune responses, and resist treatment

Over the past decades, the rapid advancement of nanotechnology has facilitated the development of various Bi-based CAs, including Bi [17,18,19,20], Bi 2 S 3 [21,22,23], Bi 2 Se 3 [24,25,26,27], Bi 2 O 3 [28,29,30,31], BiF 3 [32,33,34], BiOI [35,36,37] Bi-DTPA [38,39,40,41], Bi 2 WO 6 [42,43,44] and other Bi-based nanomaterials [45,46,47]