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Antioxidant defense system During oxidative stress and other stress conditions increased levels of H 2 O 2 is associated with elevated production of antioxidant enzymes 31

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The results of the determination of the compounds are shown in Table 4 below, and the corresponding EC for each compound is shown 50 Compared to the corresponding EC50 for WS-3 and reported as a ratio

The production of CO, Fe 2+ , and BR is also promoted, which are products that protect neuronal cells from ischemic and hypoxic damage, maintain iron homeostasis, and reverse the progression of VaD through multiple pathways (Chiang et al., 2021)

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