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Activating these receptors triggers a signaling cascade that upregulates hormone-sensitive lipase, which breaks down stored triglycerides into free fatty acids and glycerol essentially mobilizing stored fat for use as energy

Published studies have investigated its potential role in: metabolic regulation adipocyte biology nicotinamide metabolism methylation pathways NAD biology ageing biology oncology research These are active areas of scientific investigation rather than established clinical applications

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The effects of B12 injections may last several weeks , with maintenance treatments recommended for continued benefits