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Analysis of the surviving cells in the HIV-infected cultures by transmission electron microscopy (TEM) demonstrated that mitochondria in the surviving HIV infected cells had become bigger (Fig

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Acitretin impairs mitochondrial phosphorylation efficiency, decreases ATP synthesis, and triggers calcium-mediated permeability transition (MPT), resulting in apoptosis and necrosis

The effect of culture medium was not significant on day 1 (Holm-dks multiple comparisons test, P = 0.4) but there was a significant increase in AP activity in differentiation medium compared to proliferation medium at both day 2 ( P = 0.002) and day 3 ( P = 0.03) (Figure 1A)

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