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This late gate configuration is close to the optimal one at 765 nm reported by 22 for TD-DCS monitoring of cerebral blood flow, where they claim that gate start times varying from 300 to 400 ps with respect to the peak of temporal point spread function and widths of 500 ps and above correspond to both high contrast-to-noise ratio and high intrinsic sensitivity

Despite decades of work, the precise receptor and mechanism are still not fully established

Similarly, diminished CYP heme results in its low activity to alter, among other things, drug and xenobiotic metabolism

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